Web10. nov 2024 · The 2.53 version of TOPCAT is available as a free download on our software library. TOPCAT can be installed on Windows XP/Vista/7 environment, 32-bit version. The … Web24. jún 2024 · Purpose of Review Spironolactone did not demonstrate benefit with respect to the primary composite endpoint in the global TOPCAT (Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist) trial in patients with chronic heart failure with preserved ejection fraction (HFpEF). We identify key lessons from the …
Treatment of Preserved Cardiac Function Heart Failure …
WebThe TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist Trial) trial randomized patients with HFpEF and either prior hospitalization for HF or elevated natriuretic peptide levels (B-type NP [BNP] ≥100 pg/ml or N-terminal proBNP ≥360 pg/ml) to spironolactone or placebo. Web10. apr 2014 · Aldosterone Antagonist (TOPCAT) trial is provided in the Supplementary Appen-dix, available at NEJM.org. This article was updated on April 10, 2014, at … pineapple keychain wooden
Regional Variation in Patients and Outcomes in the ... - Circulation
Web15. okt 2004 · Cardiac structure and function and prognosis in heart failure with preserved ejection fraction: findings from the echocardiographic study of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) Trial. Circ Heart Fail. 2014 Sep;7(5):740-51. doi: 10.1161/CIRCHEARTFAILURE.114.001583. Epub 2014 … Web18. nov 2013 · The TOPCAT trial showed that spironolactone is not superior to placebo in improving CV outcomes in patients with HFpEF, with higher rates of hyperkalemia and … Web23. nov 2024 · We assessed the effects of spironolactone in patients with HFpEF with resistant hypertension using data from the TOPCAT study. 11 A detailed description of the study protocol, design, and patient characteristics has been reported previously. 6, 11, 12 Briefly, TOPCAT was an international, multicenter, randomized, double‐blind, placebo ... pineapple keyboard stickers